
Endometrial Scratching in Failed IVF Cycles
When couples undergo IVF, they often hope for success on the first try. While we have high success rates, some may need multiple cycles to achieve a pregnancy.
Even when doctors transfer good-quality embryos, the cycle might still not succeed. Researchers have explored various medical approaches to enhance endometrial receptivity, including endometrial scratching.
What is Endometrial Scratching?
Endometrial scratching is a procedure that helps the endometrium become more receptive. This can increase the chances of success in IVF patients.
Also known as endometrial injury, this technique involves intentionally disrupting the endometrium. Doctors typically recommend it for patients who have experienced multiple failed IVF cycles, even after transferring good-quality embryos. The idea behind this procedure is that disrupting the endometrium may enhance the likelihood of embryo implantation.

When Should Endometrial Scratching Be Performed?
Doctors typically perform endometrial scratching around day 21 of the menstrual cycle, during the luteal phase. This timing is about a week after ovulation and a week before the next expected period. Couples need to avoid unprotected intercourse during this cycle, as the procedure may harm an existing pregnancy.

How is endometrial scratching performed?
Doctors can perform endometrial scratching with different types of instruments. The most common is the endometrial biopsy procedure, generally done with a thin, flexible plastic tube and pipelle catheter. The pipelle goes through the cervix and into the uterus. It moves up and down and rotates to create disruption.
Doctors can perform this simple and affordable procedure in an outpatient department. You don't need any anaesthesia, and you can perform it in less time. It might cause some discomfort or pain.
How Does Endometrial Scratching Work?
Endometrial scratching is believed to work through several mechanisms:
- A local scratch in the endometrium may trigger decidualization, enhancing its receptivity to embryos.
- It could release cytokines and growth factors that promote wound healing, which is beneficial for implantation.
- It may aid in the maturation of the endometrium.
At Dr Arockia Virgin Fernando Fertility Clinic, we take pride in our high success rates for infertility treatments. For patients who have experienced previous failures at other centres, we are happy to review your medical history and IVF records. We look forward to supporting you on your journey to motherhood.